This report provides comprehensive information on the therapeutic development for Smallpox, complete with comparative analysis at various stages.
Smallpox was one of the world’s most dangerous killers for a very long time. In 1980, it was decided that smallpox would be eradicated form the world. All countries eventually stopped vaccination and since then no case of smallpox has been detected for 35 years. But recently it has been found that six vials of smallpox have been found in the National Institutes of Health campus in Bethesda, Maryland. Fortunately the vials were moved to an isolated and secure location.
For a long time the smallpox vaccine is the only smallpox treatment known to man to prevent the disease in an already exposed person.
This report, Smallpox - Pipeline Review, H2 2014, provides comprehensive information on the therapeutic development for smallpox, along with latest updates and key players.
No treatment has yet been approved by the US Food and Drug Administration (FDA) for smallpox, and thus the only prevention is vaccination. Certain medications, including topical idoxuridine and cidofovir, can be applied under investigational new drug (IND) protocol for better management of the smallpox treatment. Bacterial infections of the skin on the other hand can be treated with semisynthetic penicillins or first-generation cephalosporins or even clindamycin. In some cases Ampicillin or amoxicillin can also be used.
Research to assess new antiviral agents for the treatment of smallpox is still in the research phase. Recent research suggests that the drug cidofovir (Vistide) may fight the virus. Smallpox research scientists are carrying out studies with animals to fathom the drugs capability to treat the disease.
In addition to these efforts recently, the National Institute of Allergy and Infectious Diseases (NIAID) have applied to the US Food and Drug Administration (FDA) to use the antiviral drug cidofovir for the smallpox treatment.
A lot of companies are investing in research and development of drugs to prevent the disease. The key players in the smallpox treatment market are Inovio Pharmaceuticals, Inc., Bavarian Nordic A/S, Symphogen A/S , Nanotherapeutics, Inc., CEL-SCI Corporation, SIGA Technologies, Inc., TapImmune Inc., CJ CheilJedang Corp., MacroGenics, Inc., AlphaVax, Inc., EpiVax, Inc., Chimerix, Inc., Conkwest, Inc., Inhibikase Therapeutics, Inc., and Polyrizon Ltd.
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Smallpox treatment, smallpox drugs